WHAT BLOOD TELLS US: CHARACTERISTICS BEYOND ITS COLOR
DOI:
https://doi.org/10.47230/unesum-ciencias.v10.n1.2026.309-319Keywords:
blood groups, hematological diseases, transfusion, hematological diseases, transfusionAbstract
With a peculiar red hue, blood is a common tissue of all vertebrates. As part of its functions, blood provides oxygen and nutrients to all the body’s organs in addition to removing toxic waste. Althoug in general terms in humans’ blood is the same between individuals, there are important differences related to the genetic bases of each person. These differences determine the classification of individuals in a particular way and in polulation groups, and also establish the propensity of people to suffer certain diseases. Blood has been considered a life enhancer in different cultures and, considering its particularities, it is. Here, we review some characteristics of blood and the pathologies to which it is expossed. Its importance in transfusion processes is also noted.
Downloads
References
Berntorp, E., Fischer, K., Hart, D., Mancuso, M., Stephensen, D., Shapiro, A., & Blanchette, V. (2021). Haemophilia. Nat Rev Dis Primers, 27(1), 45. doi:10.1038/s41572-021-00278-x
Blann, A., & Ahmed, N. (2022). Blood Science: Principles and Pathology. John Wiley & Sons.
Buzzi, A. (2015). Karl Landsteiner y los grupos sanguíneos. ALMA Cultura y Medicina, 1(1), 50-60.
Buzzi, A. (2016). La circulación de la sangre a 400 años de su descubrimiento. Rev. Arg. Cardiol., 84(6), 595-600.
Chen, M.-H., Raffield, L., Mousas, A., Sakaue, S., Huffman, J., Moscati, A., . . . Akbari, P. (2020). Trans-ethnic and ancestry-specific blood cell genetics in 746 667 individuals from 5 global populations. Cell, 182, 1198-1213. doi:10.1016/j.cell.2020.06.045
Díaz-Matallana, M., Márquez-Benítez, Y., Martínez-Lozano , J., Briseño-Balcázar, I., Benavides-Benítez, E., & Bernal, J. (2021). Anemia falciforme: una revisión sobre el genotipo de la enfermedad, haplotipos, diagnóstico y estudios asociados. Revista médica de Chile(149), 1322-1329.
Elendu, C., Amaechi, D., Alawake-Ojimba, C., Elendu, T., Elendu, R., Ayabazu, C., . . . Adenikinju, J. (2023). Understanding Sickle cell disease: causes, symptoms, and treatment options. Medicine (Baltimore), 102(38), e35237. doi:10.1097/MD.0000000000035237.
Harmening, D., Woslager, C., & Del Toro , C. (2024). Introduction to Clinical Hematology. En D. Harmening, & L. Hutson (Edits.), Clinical Hematology and Fundamentals of Hemostasis (6a. ed.). Philadelphia, E.U.A.: F.A. Davis Company.
Haybar, H., Pezeshki, S., & Saki, N. (2019). Evaluation of complete blood count parameters in cardiovascular diseases: An early indicator of prognosis? Exp. Mol. Path.(110), 104267. doi:10.1016/j.yexmp.2019.104267
Hoffman, R., Benz, E., Silberstein, L., Heslop, H., Weitz, J., & Salama, M. (2022). Hematology E-Book: Basic Principles and Practice. Elsevier Health Sciences.
Hu, Y., Stilp, A., McHugh, C., Rao, S., Jain, D., Zheng, X., & Lane, J. (2021). Whole-genome sequencing association analysis of quantitative red blood cell phenotypes: The NHLBI TOPMed program. Am. J. Hum. Genet., 108(5), 874-893. doi:10.1016/j.ajhg.2021.04.003
ncbi.nlm.nih.gov/gene. (21 de 08 de 2024).
Noor, N., & Asmaa, M. (2024). Karl Landsteiner (1868-1943): A verstile blood scientist. Open access, 16(9), e68903. doi:10.7759/cureus.68903
Osho Olanrewaju, P., Gbajuola Joy, P., & Matthew, O. (2023). Blood Group System: Clinical Insight and Relevance in Medical Practice. European Journal of Health Sciences, 9(1), 1-11. doi:10.47672/ejhs.1425
Paucar Osorio, M. (2022). Amplitud de distribución eritrocitaria y el riesgo de mortalidad en pacientes hospitalizados con COVID-19 en el Hospital Nacional Hipólito Unanue durante el 2020. info:eu-repo/semantics/bachelorThesis. (U. R. URP, Ed.) Lima, Perú. Obtenido de https://hdl.handle.net/20.500.14138/5095
Raffield, L., Ulirsch, J., Naik, R., Lessard, S., Handsaker, R., Jain, D., & Kang, H. (2018). Commond a-globin variants modify hematologic and other clinical phenotypes in sickle cell trait and disease. PLoS Genet., 14(3), e1007293. doi:10.1371/journal.pgen.1007293
Smit Sibinga, C. (2022). Transfusion Medicine: From AB0 to AI (Artificial Intelligence). En S. Lin Linwood (Ed.), Digital Health. Brisbane, Australia: Exon publicatios.
Thompson, P., & Strandenes, G. (2019). The history of fluid resuscitation for bleeding. Damage Control Resuscitation: Identification and Treatment of Life-Threatening Hemorrhage(6), 3-29. doi:10.1007/978-3-030-20820-2_1
Vuckovic, D., Bao, E., Akbari, P., Lareau, C., Mousas, A., Jiang, T., & Chen, M.-H. (2020). The polygenic and monogenic basis of blood traits and diseases. Cell, 182, 1214-1231. doi:10.1016/j.cell.2020.08.008
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2025 Dulce María Delgadillo Álvarez, Candelaria Merino Jiménez, Candelaria Merino Jiménez
This work is licensed under a Creative Commons Attribution 4.0 International License.
